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森 博幸(准教授)

  1. タンパク質膜透過・膜組み込み機構の研究
  1. Tsukazaki, T.*, Mori, H.*, Echizen, Y., Ishitani, R., Fukai, S., Tanaka, T., Perederina, A., Vassylyev, D. G., Kohno, T., Matsurana, A. D., Ito, K. and Nureki O. Structure and function of a membrane component SecDF that enhances protein export. Nature 474, 235-238 (2011) *These authors contributed equally to this work.
  2. Tsukazaki, T.*, Mori, H.*, Fukai, S., Ishitani, R., Mori, T., Dohmae, N., Perederina, A., Sugita, Y., Vassylyev, D. G., Ito, K. and Nureki O. Conformational transition of Sec machinery inferred from bacterial SecYE structures. Nature 455, 988-991 (2008) *These authors contributed equally to this work.
  3. Vassylyev, D. G., Mori, H., Vassylyeva, M. N., Tsukazaki, T., Kimura Y., Tahirov, H. T. and Ito K. Crystal structure of the translocation ATPase SecA from Thermus thermophilus reveals, a parallel, head-to-head dimer. J. Mol. Biol. 364, 248-258 (2006)
  4. Mori H. and Ito, K. The long alpha-helix of SecA is important for mechanoconversion of its ATPase engine. J. Biol.Chem. 281, 36249-36256 (2006)
  5. Mori, H. and Ito, K. Different modes of SecY-SecA interactions revealed by site-directed in vivo photo-cross-linking. Proc. Natl. Acad. Sci. USA. 103, 16159-16164 (2006)
  6. Mori, H., Shimokawa, N., Satoh, Y. and Ito, K. Mutational analysis of transmembrane regions 3 and 4 of SecY, a central component of protein translocase. J. Bacteriol. 186, 3960-3969 (2004)
  7. Mori, H., Tsukazaki, T., Masui, R., Kuramitsu, S., Yokoyama, S., Johnson, A. E., Kimura, Y., Akiyama, Y. and Ito, K. Fluorescence resonance energy transfer analysis of protein translocase: SecYE from Thermus thermophilus HB8 forms a constitutive oligomer in membrane. J. Biol. Chem. 278, 14257-14264 (2003)
  8. Mori, H. and Ito, K. An essential amino acid residue in the protein translocation channel revealed by targeted random mutagenesis of SecY. Proc. Natl. Acad. Sci. USA 98, 5128-5133 (2001)
1992年 大阪大学大学院理学研究科博士課程中退
1992年 大阪大学産業科学研究所教務職員
1993年 東京薬科大学生命科学部助手
1996年 京都大学ウイルス研究所助手
2007年 京都大学ウイルス研究所准教授
部屋番号 ウイルス研究所本館2階216号室
電話番号 075-751-3995
電子メール hiromori + @virus.kyoto-u.ac.jp


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