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Department of Chemistry, Graduate School of Science, Kyoto University

Jun Shimokawa (Associate Professor)

Field of Expertise:
Organic Chemistry
Organic Synthesis
Research Interests:
  1. Development of novel chemical transformations based on the discovery of new chemical reactivity
  2. Development of novel strategies for constructing complex molecular structure
Recent Representative Publications:
  1. K. Douki, H. Ono, T. Taniguchi, J. Shimokawa, M. Kitamura, T. Fukuyama, “Enantioselective Total Synthesis of (+)-Hinckdentine A via a Catalytic Dearomatization Approach” J. Am. Chem. Soc. 2016, 138, 14578−14581.
  2. T. Harada, J. Shimokawa, T. Fukuyama, “Unified Total Synthesis of Five Gelsedine-type Alkaloids: (–)-Gelsenicine, (–)-Gelsedine, (–)-Gelsedilam, (–)-14-Hydroxygelsenicine, and (–)-14,15-Dihydroxygelsenicine” Org. Lett. 2016, 18, 4622−4625.
  3. H. Umihara, T. Yoshino, J. Shimokawa, M. Kitamura, T. Fukuyama, “Development of a Divergent Synthetic Route to the Erythrina Alkaloids: Asymmetric Syntheses of 8-Oxo-erythrinine, Crystamidine, 8-Oxo-erythraline, and Erythraline” Angew. Chem. Int. Ed. 2016, 55, 6915−6918.
  4. J. Shimokawa, “Divergent strategy in natural product synthesis” Tetrahedron Lett. 2014, 55, 6156−6162.
  5. R. Takeuchi, J. Shimokawa, T. Fukuyama, “Development of a route to chiral epidithiodioxopiperazine moieties and application to the asymmetric synthesis of (+)-hyalodendrin” Chem. Sci. 2014, 5, 2003-2006.
  6. K. Kitahara, J. Shimokawa, T. Fukuyama, “Stereoselective Synthesis of Spirotryprostatin A” Chem. Sci. 2013, 4, 904−907.
  7. Y. Iwai, T. Ozaki, R. Takita, M. Uchiyama, J. Shimokawa, T. Fukuyama, “Modified McFadyen–Stevens reaction for a versatile synthesis of aliphatic/aromatic aldehydes: design, optimization, and mechanistic investigations” Chem. Sci. 2013, 4, 1111−1119.
  8. K. Chiyoda, J. Shimokawa, T. Fukuyama, “Total Syntheses of All the Amathaspiramides” Angew. Chem. Int. Ed. 2012, 51, 2505−2508.
  9. J. Shimokawa, T. Harada, S. Yokoshima, T. Fukuyama, “Total Synthesis of Gelsemoxonine” J. Am. Chem. Soc. 2011, 133, 17634−17637.
  10. T. Yamakawa, E. Ideue, J. Shimokawa, T. Fukuyama, “Total Synthesis of Tryprostatins A and B” Angew. Chem. Int. Ed. 2010, 49, 9262–9265.
Education:
B.S. (2003) & M.S. (2005) from the University of Tokyo (Mentor: Prof. Yuichi Hashimoto)
Ph.D. (2011) from the University of Tokyo (Mentor: Prof. Tohru Fukuyama)
Professional Appointments:
2006-2012 Assistant Professor, Graduate School of Pharmaceutical Sciences, The University of Tokyo
2012-2017 Assistant Professor, Graduate School of Pharmaceutical Sciences, Nagoya University
2018 -present Associate Professor, Graduate School of Science, Kyoto University
Awards:
Young Scientist’s Research Award in Natural Product Chemistry (2012)
Thieme Chemistry Journals Award 2014 (2013)
Mitsubishi Tanabe Pharma Corporation Award in Synthetic Organic Chemistry, Japan (2014)
Asian Core Program/Advanced Research Network Lectureship Award, China (2016)
Asian Core Program/Advanced Research Network Lectureship Award, Malaysia (2016)
The Pharmaceutical Society of Japan Award for Young Scientists (2017)
Chemist Award BCA 2017 (2017)
Contact Information:
Phone: +81-75-753-3986
Fax: +81-75-753-3988
E-mail: shimokawa + @kuchem.kyoto-u.ac.jp
Link:
Research Group Website

This page was last modified on 04 January 2018.

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