Masahiro Fujihashi (Assistant Professor)

Field of Expertise

Structural Biology

Protein Crystallography

Research Interest

1. Mechanisms of biological macromolecular functions
2. Alternation of biological macromolecular functions
3. Development of protein crystallography techniques

Selected Papers

1. "Structural characterization of the molecular events during a slow substrate-product transition in orotidine 5'-monophosphate decarboxylase."
   Fujihashi, M., Wei, L., Kotra, L.P. & Pai, E.F. (2009) J Mol Biol. 387, 1199-210
2. "Crystal structure of archaeal photolyase from Sulfolobus tokodaii with two FAD molecules: implication of a novel light-harvesting cofactor."
   Fujihashi, M., Numoto N, Kobayashi Y, Mizushima A, Tsujimura M, Nakamura A, Kawarabayasi Y, Miki K. (2007) J Mol Biol. 365, 903-10.
3. "An unprecedented twist to ODCase catalytic activity";
   Fujihashi, M., Bello, A.M., Poduch, E., Wei, L., Annedi, S.C., Pai, E.F.& Kotra, L.P. (2005). J Am Chem Soc 127, 15048-50.
4. "Crystal structure of fucose-specific lectin from Aleuria aurantia binding ligands at three of its five sugar recognition sites";
   Fujihashi, M., Peapus, D.H., Kamiya, N., Nagata, Y.& Miki, K. (2003). Biochemistry 42, 11093-9.
5. "Crystal structure of cis-prenyl chain elongating enzyme, undecaprenyl diphosphate synthase";
   Fujihashi, M., Zhang, Y.W., Higuchi, Y., Li, X.Y., Koyama, T.& Miki, K. (2001). Proc Natl Acad Sci U S A 98, 4337-42.

Contact Information

Phone: 81(Japan)-75-753-4030
Fax: 81(Japan)-75-753-4032
Email: mfuji + @ kuchem.kyoto-u.ac.jp

Links

Biological Structural Chemistry (internal site)
Laboratory website
Personal website

This page was last modified on 13 August 2011.