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Department of Chemistry, Graduate School of Science, Kyoto University

Keiji MARUOKA (Professor)

Field of Expertise:
Organic Chemistry,
Organic Synthesis,
Organocatalytic Chemistry
Research Interests:
  1. Design of chiral phase transfer catalysts for useful amino acid synthesis
  2. Design of high-performance organocatalysts for selective organic synthesis
  3. Chemistry of bidentate Lewis acids and its synthetic application
Recent Papers:
  1. T. Kano, R. Sakamoto, M. Akakura, and K. Maruoka, "Stereocontrolled Synthesis of Vicinal Diamines by Organocatalytic Asymmetric Mannich Reaction of N-Protected Aminoacetaldehydes: Formal Synthesis of (-)-Agelastatin A", J. Am. Chem. Soc., 134, 7516 (2012).
  2. S. Shirakawa, K. Liu, and K. Maruoka, "Catalytic Asymmetric Synthesis of Axially Chiral o-Iodoanilides by Phase-Transfer Catalyzed Alkylations", J. Am. Chem. Soc., 134, 916 (2012).
  3. S. A. Moteki, J. Han, S. Arimitsu, M. Akakura, K. Nakayama, and K. Maruoka, "An Achiral-Acid-Induced Switch in the Enantioselectivity of a Chiral cis-Diamine-Based Organocatalyst for Asymmetric Aldol and Mannich Reactions ", Angew. Chem., Int. Ed., 51, 1187 (2012).
  4. T. Kano, H. Sugimoto, and K. Maruoka, " Efficient Organocatalytic Cross-Aldol Reaction between Aliphatic Aldehydes through their Functional Differentiation", J. Am. Chem. Soc., 133, 18130 (2011).
  5. T. Hashimoto, H. Kimura, Y. Kawamata, and K. Maruoka, "Generation and Exploitation of Acyclic Azomethine Imines in Chiral Brønsted Acid Catalysis", Nature Chem., 3, 642 (2011).
  6. L. Wang, S. Shirakawa, and K. Maruoka, "Asymmetric Neutral Amination of Nitroolefins Catalyzed by Chiral Bifunctional Ammonium Salts in Water-Rich Solvent", Angew. Chem., Int. Ed., 50, 5327 (2011).
  7. S. A. Moteki, S. Xu, S. Arimitsu, and K. Maruoka, "Design of Structurally Rigid trans-Diamine-Based Tf-Amide Organocatalysts with a Dihydroanthracene Framework for Asymmetric Conjugate Additions of Heterosubstituted Aldehydes to Vinyl Sulfones", J. Am. Chem. Soc., 132, 17074 (2010).
  8. R. He, S. Shirakawa, and K. Maruoka, "Enantioselective Base-Free Phase-Transfer Reaction in Water-Rich Solvent", J. Am. Chem. Soc., 131, 16620 (2009).
  9. T. Kano, H. Mii, and K. Maruoka, " Direct Asymmetric Benzoyloxylation of Aldehydes Catalyzed by 2-Tritylpyrrolidine", J. Am. Chem. Soc., 131, 3450 (2009).
  10. K. Nakayama and K. Maruoka, "Complete Switch of Product Selectivity in Asymmetric Direct Aldol Reaction with Two Different Chiral Organocatalysts from a Common Chiral Source", J. Am. Chem. Soc., 130, 17666 (2008).
Education:
B.S. Department of Industrial Chemistry, School of Engineering, Kyoto University 1976
Ph.D. Department of Chemistry, University of Hawaii 1980
Professional Appointments:
1980—1985 Assistant Professor School of Engineering, Nagoya University
1985—1989 Lecturer School of Engineering, Nagoya University
1990—1995 Associate Professor School of Engineering, Nagoya University
1995—2000 Professor Graduate School of Science, Hokkaido University
2000—2001 Professor Graduate School of Science, Kyoto University and Hokkaido University
2001—present Professor Graduate School of Science, Kyoto University
2009—present Hold “Organocatalytic Chemistry Special Laboratory”
Awards:
1985 The Japan Chemical Society Award for Young Chemist
2000 The Inoue Prize for Science
2001 The Ichimura Prize for Science
2003 Japan Synthetic Organic Chemistry Award
2004 Nagoya Silver Medal
2006 The Green and Sustainable Chemistry Award
2006 Award by the Minister of Education, Culture, Sports, Science and Technology
2007 The Japan Chemical Society Award
2007 Molecular Chirality Award
2007/2008 Novartis Lectureship Award
2010 The Chunichi Cultural Prize
2011 Arthur C. Cope Scholar Award
2011 Medal with Purple Ribbon (National Prize)
2011 Humboldt Research Award
2012 Toray Science and Technology Prize
2012 The Kyoto Shimbun Award for the Arts, Science and Culture
2002—present Editorial Advisory Board of Organic & Biomolecular Chemistry
2005—2007 Board of Director of Journal of the Synthetic Organic Chemistry, Japan
2005—present Fellow of the Royal Society of Chemistry
2006—present Editorial Advisory Board of Chemistry: An Asian Journal
2006—2007 Editorial Advisory Board of Chemical Communications
2007—present Editorial Board of Chemical Communications
2007—present Editorial Advisory Board of The Open Organic Chemistry Journal
2009—present Editorial Advisory Board of Accounts of Chemical Research
2011—present Editor of The Chemical Record
2011—present Editorial Advisory Board of Advanced Synthesis & Catalysis
2012—present Regional Editor of Tetrahedron Letters
2012—present Co-Chairperson and Editor of Asian Journal of Organic Chemistry
Group-Project Leader of the Scientific Research on Priority Areas “Advanced Molecular Transformations of Carbon Resources” (Term: October 2005 ~ March 2009)
Leader of the Specially Promoted Research "High-Performance Organocatalyst Project" (Term: May 2009 ~ March 2014)
Contact Information:
Phone: 81(Japan)-75-753-4041
Fax: 81(Japan)-75-753-4041
E-mail: maruoka + @kuchem.kyoto-u.ac.jp
Link:
Synthetic Organic Chemistry Laboratory (internal link)
Maruoka Group web site

This page was last modified on 05 February 2013.

© Kyoto University 2008