Toshikazu Bando (Associate Professor)

Field of Expertise:

Chemical Biology,

Organic Chemistry

Research Interests:

1. Design, Synthesis and Evaluation of Biological-functional molecules

Recent Papers:

1. G. Kashiwazaki, T. Bando, K. Shinohara, M. Mioshima, H. Kumamoto, S. Nishijima, H. Sugiyama, Alkylation of a Human Telomere Sequence by Heterotrimeric Chlorambucil PI Polyamide Conjugates. Bioorg Med. Chem., 2010, 18,2887-2893.
2. G. Kashiwazaki, T. Bando, K. Shinohara, M. Minoshima, S. Nishijima, H. Sugiyama, Cooperative alkylation of double-strand human telomere repeat sequences by PI polyamides with 11-base-pair recognition based on a heterotrimeric design, Bioorg. Med. Chem. 2009, 17, 1393-1397.
3. T. Bando, M. Minoshima, G. Kashiwazaki, K, Shinohara, S. Sasaki, J.Fujimoto, A. Ohtsuki, M. Murakami, S. Nakazono, H. Sugiyama, Requirement of β-alanine components in sequence-specific DNA alkylation by pyrrole-imidazole conjugates with seven-base pair recognition, Bioorg. Med. Chem., 2008, 16, 2286-2291.
4. T. Bando, J. Fujimoto, M. Minoshima, K. Shinohara, S. Sasaki, G. Kashiwazaki, M. Mizumura, H. Sugiyama, Detection of CAG repeat DNA sequences by pyrene-functionalized pyrrole-imidazole polyamides, Bioorg. Med. Chem., 2007, 15, 6937-6942.
5. T. Bando, S. Sasaki, M. Minoshima, C. Dohno, K. Shinohara, A. Narita, H. Sugiyama, Efficient DNA Alkylation by a Pyrrole-Imidazole CBI Conjugate with an indole Linker: Sequence Specific Alkylation with Nine-Base-Pair Recognition, Bioconjugate Chem. 2006, 17, 715-720.
6. T. Bando, H. Sugiyama, Synthesis and Biological Properties of Sequence-Specific DNA-Alkylating Pyrrole-Imidazole Polyamides, Acc. Chem. Res., 2006, 39, 935-944.

Contact Information:

Phone: 81(Japan)-75-753-4001
Fax: 81(Japan)-75-753-3670
E-mail: bando + @kuchem.kyoto-u.ac.jp

Link:

Chemical Biology Laboratory (internal link)
Sugiyama Laboratory

This page was last modified on 05 April 2018.