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Department of Chemistry, Graduate School of Science, Kyoto University

Asako Yamayoshi (Associate Professor (Hakubi Center))

Field of Expertise:
Chemical Biology, Medicinal Chemistry
Research Interests:
  1. Development of functional molecules to regulate non-coding RNA
  2. Novel photodynamic strategy to regulate epigenetic gene expression
Recent Papers:
  1. Effective anti-miRNA oligonucleotides show high releasing rate of microRNA from RNA-induced silencing complex (RISC). Ariyoshi J.; Matsuyama Y.; Kobori A.; Murakami A.; Sugiyama H.; Yamayoshi A.* Nucleic Acid Therapeutics, 2017, 27, 303-308.
  2. Selective and Robust Stabilization of Triplex DNA Structures using Cationic Comb-type Copolymers. Yamayoshi, A.*; Miyoshi, D.; Zouzumi, Y.; Matsuyama, Y.; Ariyoshi, J.; Shimada, N.; Murakami, A.; Wada, T.; Maruyama, A.* Phys. Chem., 2017, 121, 4015−4022.
  3. Development of Novel Antisense Oligonucleotides for the Functional Regulation of RNA-Induced Silencing Complex (RISC) by Promoting the Release of microRNA from RISC. Ariyoshi, J.; Momokawa, D.; Eimori, N.; Kobori, A.; Murakami A.; Yamayoshi, A.* Bioconjugate Chemistry, 2015, 26, 2454-2460.
  4. Novel photodynamic effect of psoralen-conjugated oligonucleotides for discrimination of methylation of cytosine in DNA. Yamayoshi, A.*; Matsuyama, Y.; Kushida, M.; Kobori, A.; Murakami A. Photochemistry and Photobiology, 2014, 90,716-722.
  5. Functional regulation of RNA-induced silencing complex by photoreactive oligonucleotides. Matsuyama, Y.; Yamayoshi, A.*; Kobori, A.; Murakami A. Bioorg Med Chem, 2014, 22,1003-1007.
Educational Background:
2000~2003 Ph.D. Student at the Department of Bioengineering, Kyoto Institute of Technology
2003~2005 Postdoctral Fellow at the Medical Institute of Bioregulation, Kyushu University
2005~2007 Research Associate Professor at the Institute of Material Chemistry and Engineering, Kyushu University
2007~2015 Assistant Professor at the Department of Bioengineering, Kyoto Institute of Technology
2015~ Associate Professor at the Hakubi Center for Advanced Research, Kyoto University (Cooperation Associate Professor at the Graduate School of Science, Kyoto University)
2017~ Research Director at PRESTO JST
Contact Information:
Phone: 81(Japan)-75-753-9767
Fax: 81(Japan)-75-753-9761
E-mail: asakoy + @kyoto-u.ac.jp
Link:
Chemical Biology Laboratory (internal link)
Sugiyama Laboratory

This page was last modified on 31 October 2017.

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